فوسابريبيتينت

فوسابريبيتينت
Systematic (IUPAC) name
	[3-{[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl] ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl}-5-oxo- 2H-1,2,4-triazol-1-yl]phosphonic acid
Clinical data
AHFS/Drugs.com	Multum Consumer Information
MedlinePlus	a604003
Licence data	EMA:Link, US FDA:link
Pregnancy cat.	B (US)
Legal status	POM (UK) ℞-only (US)
Routes	Intravenous
Pharmacokinetic data
Bioavailability	n/a
Protein binding	>95% (aprepitant)
Metabolism	To aprepitant
Half-life	9 to 13 hours (aprepitant)
Identifiers
CAS number	172673-20-0 ; 265121-04-8 (dimeglumine)
ATC code	A04AD12
PubChem	CID 219090
IUPHAR ligand	7623
DrugBank	DB06717
ChemSpider	189912
UNII	6L8OF9XRDC
KEGG	D06597
ChEBI	CHEBI:64321
ChEMBL	CHEMBL1199324
Chemical data
Formula	C23H22F7N4O6P
Mol. mass	614.406 g/mol
	SMILES C[C@H](c1cc(cc(c1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H](N(CCO2)Cc3[nH]c(=O)n(n3)P(=O)(O)O)c4ccc(cc4)F;
	InChI InChI=1S/C23H22F7N4O6P/c1-12(14-8-15(22(25,26)27)10-16(9-14)23(28,29)30)40-20-19(13-2-4-17(24)5-3-13)33(6-7-39-20)11-18-31-21(35)34(32-18)41(36,37)38/h2-5,8-10,12,19-20H,6-7,11H2,1H3,(H,31,32,35)(H2,36,37,38)/t12-,19+,20-/m1/s1; Key:BARDROPHSZEBKC-OITMNORJSA-N;
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