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An antiemetic is a drug that is effective against vomiting and nausea. Antiemetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anaesthetics, and chemotherapy directed against cancer.
Types of antiemetics
- 5-HT3 receptor antagonists – these block serotonin receptors in the central nervous system and gastrointestinal tract. As such, they can be used to treat post-operative and cytotoxic drug nausea & vomiting. However, they can also cause Constipation, Diarrhea, Drymouth, and Fatigue. 
- Dolasetron (Anzemet) - can be administered in tablet form or in an injection.
- Granisetron (Kytril, Sancuso) - can be administered in tablet (Kytril), oral solution (Kytril), injection (Kytril), or in a single transdermal patch to the upper arm (SANCUSO).
- Ondansetron (Zofran) - administered in an oral tablet form, oral dissolving tablet form, or in an injection.
- Tropisetron (Navoban) - can be administered in oral capsules or in injection form.
- Palonosetron (Aloxi) - can be administered in an injection or in oral capsules.
- Mirtazapine (Remeron), an antidepressant that also has antiemetic effects.[بحاجة لمصدر]
- Dopamine antagonists act in the brain and are used to treat nausea and vomiting associated with neoplastic disease, radiation sickness, opioids, cytotoxic drugs and general anaesthetics. Side effects include Muscle Spasms and Restlessness. 
- Droperidol, haloperidol, chlorpromazine, promethazine, prochlorperazine. Some of these drugs are limited in their usefulness by their extra-pyramidal and sedative side-effects.
- Metoclopramide (Reglan) also acts on the GI tract as a pro-kinetic, and is thus useful in gastrointestinal disease; however, it is poor in cytotoxic or post-op vomiting.
- Prochlorperazine (Compazine, Stemzine, Buccastem, Stemetil, Phenotil)
- NK1 receptor antagonist
- Antihistamines (H1 histamine receptor antagonists), effective in many conditions, including motion sickness, morning sickness in pregnancy, and to combat opioid nausea.
- Cannabinoids are used in patients with cachexia, cytotoxic nausea, and vomiting, or who are unresponsive to other agents. These may cause changes in perception, dizziness, and loss of coordination. 
- Cannabis - Medical marijuana, in the U.S., it is a Schedule I drug.[بحاجة لمصدر]
- Dronabinol (Marinol) - a Schedule III drug in the U.S.[بحاجة لمصدر]
- Some synthetic cannabinoids such as Nabilone (Cesamet) or the JWH series.
- Sativex is an oral spray containing THC and CBD. It is currently legal in Canada and a few countries in Europe but not legal in the U.S.[بحاجة لمصدر]
- Trimethobenzamide; thought to work on the CTZ
- Ginger - contains 5HT3 antagonists gingerols and shogaols. 
- Emetrol also claimed to be an effective antiemetic.
- Propofol given intravenously. It has been used in an acute care setting in hospital as a rescue therapy for emesis.[بحاجة لمصدر]
- Peppermint claimed to help nausea or stomach pain when added into a tea or peppermint candies.
- Muscimol purported as such. 
- Ajwain purported to be antiemetic. It is a popular spice in India, Ethiopia and Eritrea.[بحاجة لمصدر]
- Zachary A. Flake, Robert D. Scalley, Austin G. Bailey (2004 Mar 1st), "Practical Selection of Antiemetics", Am Fam Physician 69 (5): 1169–1174, 
- Abdel-Aziz H, Windeck T, Ploch M, Verspohl EJ. (2006-01-13), "Mode of action of gingerols and shogaols on 5-HT3 receptors: binding studies, cation uptake by the receptor channel and contraction of isolated guinea-pig ileum.", Eur J Pharmacol. 530 (1-2): 136–43 Epub 2005 Dec 20
- Muscimol. Chemical Data Sheet, Database of Hazardous Materials, CAMEO chemicals
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