نتائج البحث

| elimination_half-life = 0.76 hours. Active metabolite (hydroxyfasudil) 4.66 hours.

| elimination_half-life = 1-3 days (acute); 4-6 days (chronic); Active metabolite Norfluoxetine 4-16 days (acute and chronic)

...= 1.4–2.6 hours <small>(mesuximide)</small><br>28–38 hours <small>(active metabolite)</small>

| bioavailability = Absolute: 25%<br />When main metabolite desmethyldoxepin is included: 31% | elimination_half-life = Doxepin 17 hours, main metabolite Desmethyldoxepin 51 hours

| bioavailability = 52% (active metabolite) | protein_bound = 50% (active metabolite)

| metabolism = Extensively hepatic; main metabolite is inactive ...ion = Primarily bile and feces; urine (9% as unchanged drug, 4% as primary metabolite)

...principally via &beta;-oxidation of the carboxyl [[side chain]]. The main metabolite is tetranor-iloprost, which is found in the urine in free and conjugated fo

| elimination_half-life = 1&ndash;17 hours for perindoprilat (active metabolite)

| metabolism = [[Hepatic]] to inactive [[metabolite]]s

| active metabolite = [[cycloguanine]]

| protein_bound = 90% (active [[thiorphan]] metabolite)<ref name = SPC>{{cite web|title=SPC-DOC_PL 39418-0003.PDF|work=Medicines a

| elimination_half-life = 3-4 hours (parent drug)<br>8-13 hours (active metabolite)

Recent studies indicate that in fact the primary metabolite of tienilic acid (5-OH tienilic acid) cannot be derived from a thiophene-S-

| excretion = Fecal (40-75%) and [[kidney]] (30% as unchanged drug and [[metabolite]]s)

| elimination_half-life = 1-2 hours, active metabolite 3 hours

| elimination_half-life = 18 hours (imatinib)<br>40 hours (active metabolite)

| protein_bound=27±2% (parent compound), 30±12% (active metabolite, [[desvenlafaxine]])<ref name=DM>{{cite web |title=Venlafaxine (venlafaxine ...15±6 h (parent compound for extended release preparations), 11±2 h (active metabolite)<ref name=TGA/><ref name=DM/>

| legal_status = OTC in Canada and US however in the us the metabolite is in [[schedule I]]

| excretion = Unchanged drug (up to 70%) and alcoholic metabolite (30%) are excreted in the urine

| elimination_half-life = 75 hours (active metabolite is 94 hours)<ref name = ABILIFY/><ref name = DM/><ref name = EMC/><ref name