سيلدينافيل

سيلدينافيل

Systematic (IUPAC) name
1-[4-ethoxy-3-(6,7-dihydro-1-methyl- 7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl) phenylsulfonyl]-4-methylpiperazine
Clinical data
Trade names	Viagra
AHFS/Drugs.com	monograph
MedlinePlus	a699015
Licence data	EMA:Link, US FDA:link
Pregnancy cat.	B (US)
Legal status	℞ Prescription only
Routes	Oral
Pharmacokinetic data
Bioavailability	40%
Metabolism	Hepatic (mostly CYP3A4, also CYP2C9)
Half-life	3 to 4 hours
Excretion	Fecal (80%) and renal (around 13%)
Identifiers
CAS number	139755-83-2 Y
ATC code	G04BE03
PubChem	CID 5281023
DrugBank	DB00203
ChemSpider	56586 Y
UNII	3M7OB98Y7H Y
KEGG	D08514 Y
ChEBI	CHEBI:58987 Y
ChEMBL	CHEMBL1737 N
Chemical data
Formula	C22H30N6O4S
Mol. mass	base: 474.6 g/mol
SMILES O=S(=O)(N1CCN(C)CC1)c4cc(C\2=N\C(=O)c3c(N/2)c(nn3C)CCC)c(OCC)cc4.O=C(O)C(O)(CC(=O)O)CC(=O)O
InChI InChI=1S/C22H30N6O4S.C6H8O7/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28;7-3(8)1-6(13,5(11)12)2-4(9)10/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12) Y Key:DEIYFTQMQPDXOT-UHFFFAOYSA-N Y
N (what is this?)  (verify)

سيلدينافيل (Sildenafil) مثبط لخميرة فوسفوداي إستيراز.