https://www.arabsciencepedia.org/w/index.php?action=history&feed=atom&title=Dentin_sialophosphoprotein_%28protein%29Dentin sialophosphoprotein (protein) - تاريخ المراجعة2026-04-24T12:52:19Zتاريخ التعديل لهذه الصفحة في الويكيMediaWiki 1.43.6https://www.arabsciencepedia.org/w/index.php?title=Dentin_sialophosphoprotein_(protein)&diff=37988&oldid=prevإدارة الموسوعة 1: مراجعة واحدة2016-11-14T04:06:28Z<p>مراجعة واحدة</p>
<p><b>صفحة جديدة</b></p><div>{{merge to|Dentin sialophosphoprotein (gene)|discuss=Talk:Dentin sialophosphoprotein (gene)#Proposed merge with Dentin sialophosphoprotein (protein)|date=June 2015}}<br />
'''Dentin sialophosphoprotein''' is the only [[protein]] produced uniquely by [[odontoblast]]s, the cells that produce [[tooth]] [[dentin]]. It is a non-[[collagen]]ous [[SIBLING proteins|SIBLING]] protein that is later cleaved into three functional proteins: [[dentin phosphoprotein]] (also known as phosphophoryn), taken from the C-terminal end, [[dentin sialoprotein]] from the N-terminal end, and dentin glycoprotein from the middle of the molecule. Their distribution in the [[collagen]] matrix of the forming dentin suggests these proteins play an important role in the regulation of mineral deposition. Additional evidence for this correlation is phenotypically manifested in patients with mutant forms of dentin sialophosphoprotein. Such patients suffer dental anomalies including type III [[dentinogenesis imperfecta]].<ref>Letty Moss-Salentijn, ''Biology of Mineralized Tissue coursenotes'', [[Columbia University College of Dental Medicine]], 2009</ref><ref>Nanci, Antonio. ''Ten Cate's Oral Histology: Development, Structure, and Function''. 7th ed. St. Louis, MO: Mosby Elsevier, 2008. Print.</ref><br />
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It is coded for by a [[Dentin sialophosphoprotein (gene)|gene of the same name]].<br />
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==References==<br />
{{Reflist}}<br />
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[[Category:Teeth]]<br />
[[Category:Extracellular matrix proteins]]<br />
[[Category:Precursor proteins]]<br />
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{{protein-stub}}</div>إدارة الموسوعة 1