MufinellaGrass363: أنشأ الصفحة ب'''Serotonin syndrome signs''' Easily annoyed, Craze, Loss of consciousness, Fits, Restlessness, Increased heart rate, Perspiration, Chill, Tremor, Mental status changes, R...'

2012-03-08T20:58:58Z

أنشأ الصفحة ب'''Serotonin syndrome signs''' Easily annoyed, Craze, Loss of consciousness, Fits, Restlessness, Increased heart rate, Perspiration, Chill, Tremor, Mental status changes, R...'

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''Serotonin syndrome signs'''

Easily annoyed, Craze, Loss of consciousness, Fits, Restlessness, Increased heart rate, Perspiration, Chill, Tremor, Mental status changes, Restlessness, Increased reflexes, Increased reflexes, Stiffness, Moving, Pain in the belly, Diarrhoea, Sweating, Increased heat, High blood pressure. All these are signs of serotonin syndrome. Almost all may come usually in the first 24 hours after taking a particular overdose of serotonin drugs.
This signs are on cognitive degree, visceral anxious system degree as well as SoNS degree.
Serotonin toxicity come usually after o.d. of serotonin drugs and drug combination which increase synaptic serotonin. Drugs that are know to stimulate high levels of serotonin are: MAOIs, TCAs, SSRIs, SNRIs, Bupropion, Tramadol, Fentany, Oxycodone, Hydrocodone, MDMA, MDA, Amphetamine, Sibutramine, Cocaine, Triptans, LSD, Panax Ginseg, Nutmed, Yohimbe, Syrian Rue, Ritonavir, Granisetron, Olanzapine, Valproate, Buspirone, Lithium, Linezolid, Dextromethorphan, Risperidone, Trypthophan, L-Dopa, Valproate, Pep pill.
Because [http://habes.ucoz.com/index/signs_of_serotonin_syndrome/0-4 serotonin toxidrome] it's not tested in the laboratory for diagnosis, signs or symptoms are the one need noticed. The best set of criteria to use to diagnose serotonin toxicity is Hunter Serotonin Toxicity Criteria.

Treatment for serotonin syndrome are as follows:
discontinuing drugs that made the overdose posible as well as drugs that can contribute
management of serotonin antagonist (eg. cyproheptadine) for sever cases of toxicity
for agitation, muscle mass hardness as well as seizure like movements, benzodiazepines (Valium, Ativan)
Intra venous liquids
Considering that serotonin syndrome is not simple to diagnose, prevention is wanted for any serotonin drugs combination that might cause 5-hydroxytryptamine toxicity.

''Dunkley, EJ, Isbister, GK, Sibbritt, D, Dawson, AH, Whyte, IM, The Hunter Serotonin Toxicity Criteria: simple and accurate diagnostic decision rules for serotonin toxicity, QJM 2003; 96:635-642
Prator BC. Serotonin syndrome. J Neurosci Nurs. 2006 Apr;38(2):102-5.
Ford MD, Clinical Toxicology. 1st ed. Philadelphia, Pa: WB Saunders; 2001:150, 522, 547, 550.''

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MufinellaGrass363: أنشأ الصفحة ب'''Serotonin syndrome signs''' Easily annoyed, Craze, Loss of consciousness, Fits, Restlessness, Increased heart rate, Perspiration, Chill, Tremor, Mental status changes, R...'