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فوسابريبيتينت - تاريخ المراجعة
2026-07-01T20:37:22Z
تاريخ التعديل لهذه الصفحة في الويكي
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سلام المجذوب: أنشأ الصفحة ب'{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 416448532 | IUPAC_name = [3-{[(2''R'',3''S'')-2-[(1''R'')-1-[3,5-bis(trifluoromethyl)phe...'
2016-02-27T12:57:18Z
<p>أنشأ الصفحة ب'{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 416448532 | IUPAC_name = [3-{[(2''R'',3''S'')-2-[(1''R'')-1-[3,5-bis(trifluoromethyl)phe...'</p>
<p><b>صفحة جديدة</b></p><div>{{Drugbox<br />
| Verifiedfields = changed<br />
| Watchedfields = changed<br />
| verifiedrevid = 416448532<br />
| IUPAC_name = [3-{[(2''R'',3''S'')-2-[(1''R'')-1-[3,5-bis(trifluoromethyl)phenyl] ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl}-5-oxo- 2''H''-1,2,4-triazol-1-yl]phosphonic acid<br />
| image = Fosaprepitant.svg<br />
| alt = Skeletal formula of fosaprepitant<br />
| width = 250<br />
| image2 = Fosaprepitant-3D-spacefill.png<br />
| alt2 = Space-filling model of the fosaprepitant molecule<br />
<br />
<!--Clinical data--><br />
| tradename = <br />
| Drugs.com = {{drugs.com|MTM|fosaprepitant}}<br />
| MedlinePlus = a604003<br />
| licence_EU = Ivemend<br />
| licence_US = Fosaprepitant<br />
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --><br />
| pregnancy_US = B<br />
| pregnancy_category = <br />
| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 --><br />
| legal_CA = <!-- / Schedule I, II, III, IV, V, VI, VII, VIII --><br />
| legal_UK = POM<br />
| legal_US = Rx-only<br />
| routes_of_administration = [[Intravenous therapy|Intravenous]]<br />
<br />
<!--Pharmacokinetic data--><br />
| bioavailability = n/a<br />
| protein_bound = >95% (aprepitant)<br />
| metabolism = To aprepitant<br />
| elimination_half-life = 9 to 13 hours (aprepitant)<br />
| excretion = <br />
<br />
<!--Identifiers--><br />
| IUPHAR_ligand = 7623<br />
| CAS_number_Ref = {{cascite|correct|??}}<br />
| CAS_number = 172673-20-0<br />
| CAS_supplemental = <br>{{CAS|265121-04-8}} ([[meglumine|dimeglumine]])<br />
| ATC_prefix = A04<br />
| ATC_suffix = AD12<br />
| PubChem = 219090<br />
| DrugBank_Ref = {{drugbankcite|changed|drugbank}}<br />
| DrugBank = DB06717<br />
| UNII_Ref = {{fdacite|changed|FDA}}<br />
| UNII = 6L8OF9XRDC<br />
| KEGG_Ref = {{keggcite|changed|kegg}}<br />
| KEGG = D06597<br />
| ChEMBL_Ref = {{ebicite|changed|EBI}}<br />
| ChEMBL = 1199324<br />
| ChEBI = 64321<br />
| ChemSpiderID = 189912<br />
<br />
<!--Chemical data--><br />
| C=23 | H=22 | F=7 | N=4 | O=6 | P=1 <br />
| molecular_weight = 614.406 g/mol<br />
| smiles = C[C@H](c1cc(cc(c1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H](N(CCO2)Cc3[nH]c(=O)n(n3)P(=O)(O)O)c4ccc(cc4)F<br />
| StdInChI = 1S/C23H22F7N4O6P/c1-12(14-8-15(22(25,26)27)10-16(9-14)23(28,29)30)40-20-19(13-2-4-17(24)5-3-13)33(6-7-39-20)11-18-31-21(35)34(32-18)41(36,37)38/h2-5,8-10,12,19-20H,6-7,11H2,1H3,(H,31,32,35)(H2,36,37,38)/t12-,19+,20-/m1/s1<br />
| StdInChIKey = BARDROPHSZEBKC-OITMNORJSA-N<br />
}}<br />
<br />
'''فوسابريبيتينت Fosaprepitant''' هو دواء مضاد للقىء، يعطى عن طريق الوريد. وهو [[طليعة دواء]] للمركب [[أبريبيتينت]] [[aprepitant]].<br />
<br />
{{بذرة}}<br />
<br />
{{Antiemetics and antinauseants}}<br />
{{Antidepressants}}<br />
{{Anxiolytics}}<br />
{{Neuropeptide agonists and antagonists}}<br />
<br />
[[Category:Antiemetics]]<br />
[[Category:NK1 receptor antagonists]]<br />
[[Category:Prodrugs]]<br />
[[Category:Morpholines]]<br />
[[Category:Phosphoramidates]]<br />
[[Category:Triazoles]]<br />
[[Category:Organofluorides]]<br />
<br />
<br />
{{gastrointestinal-drug-stub}}<br />
{{nervous-system-drug-stub}}</div>
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