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ديميتوتيازين - تاريخ المراجعة
2026-04-15T19:31:24Z
تاريخ التعديل لهذه الصفحة في الويكي
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أسيل سيوف: أنشأ الصفحة ب'{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 443778442 | IUPAC_name = 10-(2-Dimethylaminopropyl)-''N'',''N''-dimethylphenothiazine-2-...'
2017-11-13T09:20:06Z
<p>أنشأ الصفحة ب'{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 443778442 | IUPAC_name = 10-(2-Dimethylaminopropyl)-''N'',''N''-dimethylphenothiazine-2-...'</p>
<p><b>صفحة جديدة</b></p><div>{{Drugbox<br />
| Verifiedfields = changed<br />
| Watchedfields = changed<br />
| verifiedrevid = 443778442<br />
| IUPAC_name = 10-(2-Dimethylaminopropyl)-''N'',''N''-dimethylphenothiazine-2-sulfonamide<br />
| image = Dimetotiazine.svg<br />
<br />
<!--Clinical data--><br />
| tradename =<br />
| Drugs.com = {{drugs.com|international|dimetotiazine}}<br />
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --><br />
| pregnancy_US = <!-- A / B / C / D / X --><br />
| pregnancy_category =<br />
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled--><br />
| legal_CA = <!-- Schedule I, II, III, IV, V, VI, VII, VIII --><br />
| legal_UK = <!-- GSL, P, POM, CD, or Class A, B, C --><br />
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --><br />
| legal_status = Rx-only<br />
| routes_of_administration = [[Oral administration|By mouth]]<br />
<br />
<!--Pharmacokinetic data--><br />
| bioavailability =<br />
| protein_bound =<br />
| metabolism =<br />
| elimination_half-life =<br />
| excretion =<br />
<br />
<!--Identifiers--><br />
| CAS_number_Ref = {{cascite|correct|??}}<br />
| CAS_number = 7456-24-8<br />
| ATC_prefix = N02<br />
| ATC_suffix = CX05<br />
| ATC_supplemental =<br />
| PubChem = 3089<br />
| DrugBank_Ref = {{drugbankcite|changed|drugbank}}<br />
| DrugBank = DB08967 <br />
| UNII_Ref = {{fdacite|correct|FDA}}<br />
| UNII = 1FTA475ZDB<br />
| KEGG_Ref = {{keggcite|correct|kegg}}<br />
| KEGG = D07854<br />
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}<br />
| ChemSpiderID = 2979<br />
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}<br />
| StdInChI = 1S/C19H25N3O2S2/c1-14(20(2)3)13-22-16-8-6-7-9-18(16)25-19-11-10-15(12-17(19)22)26(23,24)21(4)5/h6-12,14H,13H2,1-5H3<br />
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}<br />
| StdInChIKey = VWNWVCJGUMZDIU-UHFFFAOYSA-N<br />
<br />
<!--Chemical data--><br />
| chemical_formula = <br />
| C=19 | H=25 | N=3 | O=2 | S=2 <br />
| molecular_weight = 391.55 g/mol<br />
| smiles = CC(CN1C2=CC=CC=C2SC3=C1C=C(C=C3)S(=O)(=O)N(C)C)N(C)C<br />
}}<br />
<br />
<br />
'''ديميتوتيازين Dimetotiazine'''INN<br />
<br />
==الزمرة الدوائية==<br />
<br />
[[أدوية الشقيقة]]<br />
<br />
==الوصف==<br />
<br />
هو دواء [[فينوتيازين]]ي يستعمل لعلاج ال[[شقيقة]]. <br />
<br />
وهو [[مضاد سيروتونين]]ي و[[مضاد هيستامين]]ي.<ref>{{cite journal | last1 = Shimazawa | first1 = M | last2 = Hara | first2 = H | last3 = Watano | first3 = T | last4 = Sukamoto | first4 = T | title = Effects of Ca<sup>2+</sup> Channel Blockers on Cortical Hypoperfusion and Expression of c-Fos-Like Immunoreactivity After Cortical Spreading Depression in Rats | journal = British Journal of Pharmacology | date = August 1995 | volume = 115 | issue = 8 | pages = 1359–68 | doi = 10.1111/j.1476-5381.1995.tb16624.x | pmid = 8564192 | pmc = 1908864}}</ref><br />
<br />
==مصادر==<br />
{{ثبت المراجع}}<br />
<br />
{{مستحضرات معالجة الشقيقة}}<br />
<br />
[[تصنيف:أدوية]]<br />
[[تصنيف:موسوعة الأدوية]]<br />
[[تصنيف:مضادات الشقيقة]]</div>
أسيل سيوف