https://www.arabsciencepedia.org/w/index.php?action=history&feed=atom&title=%D8%AF%D9%8A%D9%83%D8%B3%D9%8A%D8%AA%D9%8A%D9%85%D9%8A%D8%AF 2026-04-10T08:50:01Z تاريخ التعديل لهذه الصفحة في الويكي MediaWiki 1.43.6 https://www.arabsciencepedia.org/w/index.php?title=%D8%AF%D9%8A%D9%83%D8%B3%D9%8A%D8%AA%D9%8A%D9%85%D9%8A%D8%AF&diff=41204&oldid=prev 2018-05-02T12:14:33Z

<p>أنشأ الصفحة ب&#039;{{Drugbox | Verifiedfields = changed | verifiedrevid = 460779595 | IUPAC_name = 3-(1-benzyl-4-piperidyl)-3-phenylpiperidine-2,6-dione | image = Dexetimide.svg &lt;!--Clini...&#039;</p> <p><b>صفحة جديدة</b></p><div>{{Drugbox<br /> | Verifiedfields = changed<br /> | verifiedrevid = 460779595<br /> | IUPAC_name = 3-(1-benzyl-4-piperidyl)-3-phenylpiperidine-2,6-dione<br /> | image = Dexetimide.svg<br /> <br /> &lt;!--Clinical data--&gt;<br /> | tradename = <br /> | Drugs.com = {{drugs.com|international|dexetimide}}<br /> | pregnancy_AU = &lt;!-- A / B1 / B2 / B3 / C / D / X --&gt;<br /> | pregnancy_US = &lt;!-- A / B / C / D / X --&gt;<br /> | pregnancy_category = <br /> | legal_AU = &lt;!-- Unscheduled / S2 / S3 / S4 / S8 --&gt;<br /> | legal_UK = &lt;!-- GSL / P / POM / CD --&gt;<br /> | legal_US = &lt;!-- OTC / Rx-only --&gt;<br /> | legal_status = <br /> | routes_of_administration = <br /> <br /> &lt;!--Pharmacokinetic data--&gt;<br /> | bioavailability = <br /> | protein_bound = <br /> | metabolism = <br /> | elimination_half-life = <br /> | excretion = <br /> <br /> &lt;!--Identifiers--&gt;<br /> | CAS_number_Ref = {{cascite|changed|??}}<br /> | CAS_number = 21888-98-2<br /> | ATC_prefix = N04<br /> | ATC_suffix = AA08<br /> | PubChem = 30843<br /> | IUPHAR_ligand = 354<br /> | DrugBank_Ref = {{drugbankcite|changed|drugbank}}<br /> | DrugBank = DB08997<br /> | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}<br /> | ChemSpiderID = 28615<br /> | UNII_Ref = {{fdacite|correct|FDA}}<br /> | UNII = 43477QYX3D<br /> | KEGG_Ref = {{keggcite|correct|kegg}}<br /> | KEGG = D03711<br /> | ChEMBL_Ref = {{ebicite|changed|EBI}}<br /> | ChEMBL = 1908364<br /> <br /> &lt;!--Chemical data--&gt;<br /> | C=23 | H=26 | N=2 | O=2 <br /> | molecular_weight = 362.465 g/mol<br /> | smiles = O=C2NC(=O)CCC2(c1ccccc1)C4CCN(Cc3ccccc3)CC4<br /> | StdInChI_Ref = {{stdinchicite|correct|chemspider}}<br /> | StdInChI = 1S/C23H26N2O2/c26-21-11-14-23(22(27)24-21,19-9-5-2-6-10-19)20-12-15-25(16-13-20)17-18-7-3-1-4-8-18/h1-10,20H,11-17H2,(H,24,26,27)/t23-/m1/s1<br /> | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}<br /> | StdInChIKey = LQQIVYSCPWCSSD-HSZRJFAPSA-N<br /> }}<br /> <br /> &#039;&#039;&#039;ديكسيتيميد &#039;&#039;&#039; (الاسم التجاري Tremblex) هو [[مضاد كولين]] [[ببيريدين]]ي. وهو مضاهي [[موسكارين]]ي يستعمل لعلاج [[داء باركنسون]] المحدث بسبب الأدوية. تم اكتشافه من قبل Janssen Pharmaceutica في عام 1968.&lt;ref&gt;{{Cite journal <br /> | last1 = Dom | first1 = R. <br /> | last2 = Van Lommel | first2 = R. <br /> | last3 = Baro | first3 = F. <br /> | title = A quantitative study of neuroleptic-induced extrapyramidal symptoms and their response to dexetimide, a potent and long-acting antiparkinsonian agent <br /> | journal = Acta Psychiatrica Scandinavica <br /> | volume = 47 <br /> | issue = 4 <br /> | pages = 399–410 <br /> | year = 1971 <br /> | pmid = 4947805<br /> | doi=10.1111/j.1600-0447.1971.tb03697.x<br /> }}&lt;/ref&gt;&lt;ref&gt;{{Cite journal <br /> | last1 = Huygens | first1 = H. <br /> | last2 = Vereecken | first2 = J. L. <br /> | last3 = Tanghe | first3 = A. <br /> | title = Dexetimide (R 16470) in the control of neuroleptic-induced extrapyramidal side-effects. Its prophylactic value and duration of action <br /> | journal = Psychiatria, neurologia, neurochirurgia <br /> | volume = 76 <br /> | issue = 4 <br /> | pages = 251–259 <br /> | year = 1973 <br /> | pmid = 4581374<br /> }}&lt;/ref&gt;<br /> <br /> ==مصادر==<br /> {{مراجع}}<br /> {{أدوية معالجة داء باركنسون}}<br /> [[تصنيف:أدوية]]<br /> [[تصنيف:موسوعة الأدوية]]<br /> [[تصنيف:أدوية معالجة داء باركنسون]]</div>

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